Description

Bevantolol Hydrochloride is a selective β-1 adrenergic receptor antagonist, commonly known as a β-blocker. This high-purity pharmaceutical intermediate is critical for the research and development of cardiovascular therapeutics. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of active pharmaceutical ingredients (APIs) for hypertension and angina treatment.

Application

• Pharmaceutical API Synthesis: A key intermediate in the production of finished dosage forms of the β-blocker Bevantolol.
• Cardiovascular Research: Used in preclinical and clinical studies to investigate β-1 adrenergic receptor activity and cardioprotective effects.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Formulation Development: Employed in the development of various drug delivery systems, including tablets and capsules.
• Process Chemistry: Used in scaling up and optimizing synthetic routes for commercial pharmaceutical manufacturing.

Basic Information

Product Name	Bevantolol Hydrochloride
CAS No.	42864-78-8
Molecular Formula	C20H27NO4 • HCl
Molecular Weight	381.90 g/mol
Synonyms	1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol Hydrochloride; Bevantolol HCl; (±)-Bevantolol Hydrochloride; DL-Bevantolol Hydrochloride; N-[2-(3,4-Dimethoxyphenyl)ethyl]-N'-[2-hydroxy-3-[(3-methylphenoxy)propyl]]-1,2-ethanediamine Hydrochloride; CI-775; Sentiloc
EINECS	Contact for details

Quality Control

Our Bevantolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA), including results for identity, purity, and related substances, is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.