Description

trans-4-Fluoromethyl-2-Methyl-1,3-Dioxolane is a specialized fluorinated dioxolane derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique structure, which incorporates a fluorine atom and a protected diol functionality, making it a versatile precursor for pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries seeking to introduce fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging fluorine's ability to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the introduction of fluorine enhances biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Acts as a fluorinated component in the production of advanced liquid crystals for displays and dielectric fluids for specialized electronics.
• Polymer & Material Science: Employed as a monomer or modifying agent to create fluorinated polymers with improved chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Provides a protected, fluorinated acetonide equivalent for complex molecule construction in medicinal chemistry and chemical biology research.
• Solvent & Reaction Medium: Its specific properties may be utilized as a specialty solvent for certain fluorination reactions or high-value extraction processes.

Basic Information

Item	Details
Product Name	trans-4-Fluoromethyl-2-Methyl-1,3-Dioxolane
CAS No.	42364-34-1
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	(2R,4S)-4-(Fluoromethyl)-2-methyl-1,3-dioxolane; (2S,4R)-4-(Fluoromethyl)-2-methyl-1,3-dioxolane; 4-Fluoromethyl-2-methyl-1,3-dioxolane (trans isomer); trans-4-Fluoromethyl-2-methyl-1,3-dioxolane; Fluoromethyl methyl dioxolane; 1,3-Dioxolane, 4-(fluoromethyl)-2-methyl-, trans-
EINECS	Contact for details

Quality Control

Our trans-4-Fluoromethyl-2-Methyl-1,3-Dioxolane is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.