Description

4-Fluoro-2-Iodo-1-Nitrobenzene is a halogenated nitroaromatic compound of significant interest in advanced organic synthesis. This multi-functional building block is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and iodinated active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine and iodine substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in cross-coupling reactions and other transition metal-catalyzed processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or nonlinear optical (NLO) chromophores, due to its electron-withdrawing nitro group and heavy atom effect.
• Chemical Biology Probes: Useful for synthesizing fluorinated and radioiodinated probes for imaging and diagnostic applications, including Positron Emission Tomography (PET) tracer development.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated nitrobenzene derivatives.

Basic Information

Product Name	4-Fluoro-2-Iodo-1-Nitrobenzene
CAS No.	41860-64-4
Molecular Formula	C6H3FINO2
Molecular Weight	267.00 g/mol
Synonyms	1-Fluoro-4-iodo-2-nitrobenzene; 2-Iodo-4-fluoronitrobenzene; 4-Fluoro-2-iodonitrobenzene; 2-Nitro-4-fluoroiodobenzene; 4-Fluoro-2-iodo-1-nitrobenzene; 4-Fluoro-2-iodonitrobenzene; 2-Iodo-4-fluoro-1-nitrobenzene; 1-Iodo-3-fluoro-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Iodo-1-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.