Description

Butyl 6Alpha-Fluoro-11Beta-Hydroxy-16Alpha-Methyl-3,20-Dioxopregna-1,4-Dien-21-Oate is a high-purity synthetic corticosteroid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the development of potent anti-inflammatory and immunosuppressive agents, offering precise structural control for downstream API manufacturing. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-grade intermediate to ensure the quality and efficacy of final drug products.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of advanced corticosteroid active pharmaceutical ingredients (APIs).
• Research & Development: Enables medicinal chemistry research for novel glucocorticoid receptor modulators with targeted therapeutic profiles.
• Process Chemistry: Serves as a validated starting material or intermediate in scale-up and process optimization for GMP manufacturing.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	Butyl 6Alpha-Fluoro-11Beta-Hydroxy-16Alpha-Methyl-3,20-Dioxopregna-1,4-Dien-21-Oate
CAS No.	41767-29-7
Molecular Formula	C₂₆H₃₅FO₅
Molecular Weight	446.56 g/mol
Synonyms	Butyl 6α-Fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oate; 21-Butyryloxy-6α-fluoro-11β,17α-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 6α-Fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-butyrate; Fluocortin Butyl; SH K 203; SHK-203; Fluocortin Butylate; Fluocortin 21-Butyrate
EINECS	Contact for details

Quality Control

Our Butyl 6Alpha-Fluoro-11Beta-Hydroxy-16Alpha-Methyl-3,20-Dioxopregna-1,4-Dien-21-Oate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.