Description

Almarl CAS NO 41287-43-8 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) known chemically as a β-adrenergic blocking agent. This compound is critical for the synthesis of advanced cardiovascular medications, offering precise pharmacological activity. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of treatments for hypertension, angina, and certain cardiac arrhythmias.

Application

• Pharmaceutical API Synthesis: Core intermediate in the manufacture of β-blocker drugs.
• Cardiovascular Research: Used in preclinical and clinical studies for heart disease and hypertension.
• Formulation Development: Serves as the active ingredient in tablet, capsule, and injectable formulations.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in laboratories.
• Process Chemistry: Key building block in custom synthesis and scale-up projects for novel therapeutic agents.

Basic Information

Product Name	Almarl
CAS No.	41287-43-8
Molecular Formula	C17H27NO5S
Molecular Weight	357.47 g/mol
Synonyms	Arotinolol; Arotinolol Hydrochloride; Almarl (Trade Name); 5-[2-[[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropyl]thio]-4-thiazolyl]-2-thiophenecarboxamide; (RS)-Arotinolol; (±)-Arotinolol; YM-09538
EINECS	Contact for details

Quality Control

Our Almarl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.