Description

N1-[3-(Methylthio)Propyl]Bleomycinamide is a chemically modified derivative of the bleomycin family, a class of glycopeptide antibiotics known for their antitumor activity. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel bleomycin analogs with potentially enhanced therapeutic profiles or reduced side effects. It serves as a critical intermediate for researchers and manufacturers in the oncology and life sciences sectors focused on developing next-generation chemotherapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel bleomycin-based anticancer agents and antibiotic conjugates.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action of bleomycin derivatives.
• Antitumor Agent Development: Serves as a precursor for creating modified glycopeptides with targeted delivery capabilities or improved stability profiles.
• Bioconjugation Studies: Utilized in research for attaching bleomycin moieties to antibodies, polymers, or other targeting molecules for advanced drug delivery systems.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental studies in medicinal chemistry and molecular biology.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	N1-[3-(Methylthio)Propyl]Bleomycinamide
CAS No.	41089-03-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[3-(methylthio)propyl]-; 3'-(Methylthio)propylamine bleomycinamide; Bleomycin derivative; Bleomycin A2 amide derivative; Antibiotic derivative; Glycopeptide intermediate; Antitumor agent intermediate
EINECS	Contact for details

Quality Control

Our N1-[3-(Methylthio)Propyl]Bleomycinamide is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development purposes. We provide comprehensive analytical data, including HPLC purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is supplied with each batch, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content	Contact for details
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.