Description

1-(1,1-Difluoroethyl)-3-Nitrobenzene is a specialized fluorinated aromatic nitro compound, serving as a valuable building block in advanced organic synthesis. Its unique structure, featuring both a difluoroethyl group and a nitro substituent, makes it a critical intermediate for introducing fluorine atoms and enabling subsequent functional group transformations. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs to modulate bioavailability, metabolic stability, and receptor binding.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and environmental persistence.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials that benefit from the electronic effects of the nitro and fluorine groups.
• Chemical Derivatization: The nitro group serves as a versatile handle for reduction to amines or further functionalization, enabling the construction of complex molecular architectures.

Basic Information

Item	Details
Product Name	1-(1,1-Difluoroethyl)-3-Nitrobenzene
CAS No.	40788-04-3
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	3-Nitro-α,α-difluoroethylbenzene; 1-(1,1-Difluoroethyl)-3-nitrobenzene; m-Nitro-α,α-difluoroethylbenzene; 1-(Difluoroethyl)-3-nitrobenzene; (1,1-Difluoroethyl)-3-nitrobenzene; 40788-04-3; 3-Nitrobenzene, 1-(1,1-difluoroethyl)-
EINECS	Contact for details

Quality Control

Our 1-(1,1-Difluoroethyl)-3-Nitrobenzene is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.