Description

n-Hydroxy-3-(Trifluoromethyl)Benzamide is a specialized benzamide derivative featuring a trifluoromethyl group and a reactive N-hydroxy moiety. This compound is a valuable synthetic intermediate and building block, prized for its unique combination of structural motifs that can impart metabolic stability and modulate physicochemical properties in target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, chemical biology, and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection products.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study biological pathways and protein function.
• Metal Chelator Synthesis: The N-hydroxy group makes it a useful starting material for synthesizing hydroxamic acid-based chelating agents.
• Advanced Material Precursor: Potential use in the synthesis of specialty polymers and functional materials due to the trifluoromethyl group's properties.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects for clients.

Basic Information

Product Name	n-Hydroxy-3-(Trifluoromethyl)Benzamide
CAS No.	40069-06-5
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	3-(Trifluoromethyl)benzohydroxamic acid; N-Hydroxy-3-(trifluoromethyl)benzamide; 3-Trifluoromethylbenzohydroxamic acid; m-Trifluoromethylbenzohydroxamic acid; Benzamide, N-hydroxy-3-(trifluoromethyl)-; 3-(Trifluoromethyl)benzhydroxamic acid; 3-Trifluoromethylbenzhydroxamic acid
EINECS	Contact for details

Quality Control

Our n-Hydroxy-3-(Trifluoromethyl)Benzamide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) upon request, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.