Description

2-Trifluoromethylbenzoylacetonitrile is a high-value fluorinated organic intermediate featuring a versatile benzoylacetonitrile scaffold substituted with a trifluoromethyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. Industries that need it include pharmaceutical R&D for creating novel active ingredients, agrochemical manufacturers developing new crop protection agents, and specialty chemical producers engaged in materials science and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic processes.
• Material Science Research: Intermediate for synthesizing fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Serves as a starting point for creating fluorescent tags and molecular probes for diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Product Name	2-Trifluoromethylbenzoylacetonitrile
CAS No.	40018-10-8
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	2-(Trifluoromethyl)benzoylacetonitrile; 1-(2-Trifluoromethylphenyl)-3-oxobutanenitrile; 3-Oxo-3-(2-(trifluoromethyl)phenyl)propanenitrile; α-Acetyl-2-(trifluoromethyl)benzonitrile; 2-Trifluoromethylbenzoyl methyl cyanide; 2-(Trifluoromethyl)benzoylacetonitrile; 2-TFM-BAN; o-Trifluoromethylbenzoylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethylbenzoylacetonitrile is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.