Description

Alphasone Acetonide is a synthetic steroid derivative, specifically an acetonide prodrug of alphasone. This compound is valued for its enhanced stability and bioavailability compared to its parent molecule, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research & Development: Used in preclinical and clinical research for investigating new anti-inflammatory and immunosuppressive therapies.
• Steroid Prodrug Development: Exploited in formulation science to create prodrugs with improved pharmacokinetic profiles, such as better absorption and longer duration of action.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Alphasone Acetonide
CAS No.	4968-09-6
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	Alphasone 16,17-Acetonide; 9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione; 9α-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione; Fluocortin Butyl Acetonide (related); Alphasone 16α,17α-Acetonide
EINECS	Contact for details

Quality Control

Our Alphasone Acetonide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.