Description

19-Norcorticosterone is a key steroid intermediate and reference standard of significant importance in pharmaceutical research and development. This compound is crucial for the synthesis and analytical validation of more complex corticosteroid derivatives and related bioactive molecules. It serves the needs of pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of high-purity fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel corticosteroid drugs and their analogs.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing to ensure product identity and purity.
• Biochemical Research: Employed in metabolic pathway studies, enzyme inhibition assays, and investigations into steroid hormone biosynthesis and regulation.
• Metabolite Standard: Serves as an analytical standard for the detection and quantification of steroid metabolites in biological samples for clinical or diagnostic research.
• Fine Chemical Synthesis: Utilized in custom synthesis and the production of specialized steroid-based compounds for research purposes.

Basic Information

Product Name	19-Norcorticosterone
CAS No.	4889-84-3
Molecular Formula	C₂₁H₃₀O₄
Molecular Weight	346.46 g/mol
Synonyms	11β,21-Dihydroxy-19-norpregn-4-ene-3,20-dione; 19-Nor-11-deoxycorticosterone; 19-Nor-DOC; 11β,21-Dihydroxy-19-norprogesterone; 19-Norcortexone; 19-Nor-11β,21-dihydroxy-4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 19-Norcorticosterone is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.