Description

3-Chloro-5-Fluoronitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile aromatic scaffold with multiple reactive sites for selective functionalization, enabling the creation of complex molecular architectures. This intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated aromatic rings.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging the halogen substituents for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Intermediate for producing complex colorants and functional dyes.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions due to the presence of halogens.
• Laboratory Reagent: Used in academic and industrial R&D for method development and exploratory chemistry.

Basic Information

Product Name	3-Chloro-5-Fluoronitrobenzene
CAS No.	4815-64-9
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.54 g/mol
Synonyms	1-Chloro-3-fluoro-5-nitrobenzene; 3-Chloro-5-fluoronitrobenzene; 5-Chloro-1-fluoro-3-nitrobenzene; 3-Fluoro-5-chloronitrobenzene; Benzene, 1-chloro-3-fluoro-5-nitro-; 3-Chloro-5-fluoronitrobenzol; 3-Fluoro-5-chloronitrobenzol; 5-Fluoro-3-chloronitrobenzene
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoronitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 48 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.