Description

Tosyl-S-Benzyl-L-Cysteine is a protected cysteine derivative where the thiol group is blocked by a benzyl group and the amino group is protected by a tosyl group. This compound is a crucial building block in peptide synthesis and organic chemistry, offering precise control over reactivity and stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and other bioactive molecules.

Application

• Peptide Synthesis: Serves as a key protected intermediate for the controlled incorporation of cysteine residues into peptide chains, preventing unwanted side reactions.
• Pharmaceutical Research: Used in the research and development of therapeutic peptides, enzyme inhibitors, and drug candidates that require specific cysteine chemistry.
• Bioconjugation Chemistry: Acts as a precursor for creating thiol-reactive linkers or for introducing protected thiol handles onto biomolecules for further modification.
• Chemical Biology: Employed in the study of protein structure-function relationships and the synthesis of chemically modified peptides for probing biological mechanisms.
• Material Science: Potential use in the synthesis of functionalized polymers or surfaces where controlled thiol chemistry is required after deprotection.

Basic Information

Product Name	Tosyl-S-Benzyl-L-Cysteine
CAS No.	4703-36-0
Molecular Formula	C17H19NO4S2
Molecular Weight	365.47 g/mol
Synonyms	L-Cysteine, S-benzyl-, N-tosyl-; N-(p-Toluenesulfonyl)-S-benzyl-L-cysteine; S-Benzyl-N-tosyl-L-cysteine; N-Tosyl-S-benzyl-L-cysteine; N-Tosyl-S-benzylcysteine; Tosyl-S-benzylcysteine; (2R)-2-[(4-Methylphenyl)sulfonylamino]-3-(phenylmethylsulfanyl)propanoic acid; TBC
EINECS	225-179-5

Quality Control

Our Tosyl-S-Benzyl-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	-20° to -24° (c=1 in methanol)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.