Description

20,21-Dinor Hydrocortisone is a key synthetic steroid intermediate, specifically a modified hydrocortisone derivative. This compound is valued for its role as a versatile building block in the synthesis of more complex, high-potency pharmaceutical steroids. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new steroid-based therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid hormone metabolism, receptor binding, and enzymatic pathways.

Basic Information

Product Name	20,21-Dinor Hydrocortisone
CAS No.	4484-94-0
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	20,21-Dinorcortisol; 11β,17α,21-Trihydroxy-20,21-dinorpregn-4-ene-3,18-dione; 20,21-Bisnorhydrocortisone; 20,21-Dinor-11β,17α,21-trihydroxypregn-4-ene-3,18-dione; 20,21-Dinor-17α-hydroxycorticosterone; 20,21-Dinorcortisone; 20,21-Dinorhydrocortisone; 20,21-Dinorhydrocortisone (Cortisone derivative)
EINECS	Contact for details

Quality Control

Our 20,21-Dinor Hydrocortisone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.