Description

9,11-Epoxypregn-4-Ene-17,21-Diol-3,20-Dione 21-Acetate is a high-purity steroid derivative with significant value in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the production of specialized corticosteroid analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, process development, and analytical reference standard preparation.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex corticosteroid drugs and their derivatives.
• Research & Development: Used in academic and industrial laboratories for investigating steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Process Chemistry: Employed in the development and scale-up of synthetic routes for steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis (HPLC, GC-MS).
• Biochemical Studies: Utilized in studies exploring enzyme inhibition and the biochemical pathways of steroid hormones.

Basic Information

Product Name	9,11-Epoxypregn-4-Ene-17,21-Diol-3,20-Dione 21-Acetate
CAS No.	4383-30-6
Molecular Formula	C23H30O6
Molecular Weight	402.48 g/mol
Synonyms	9,11-Epoxy-17,21-dihydroxypregn-4-ene-3,20-dione 21-acetate; 21-Acetoxy-9,11-epoxy-17-hydroxypregn-4-ene-3,20-dione; 9,11-Epoxy-17-hydroxy-21-acetoxypregn-4-ene-3,20-dione; 9,11α-Epoxypregn-4-ene-17α,21-diol-3,20-dione 21-acetate; 9,11α-Epoxy-17α,21-dihydroxypregn-4-ene-3,20-dione 21-acetate; 21-Acetoxy-9,11α-epoxy-17α-hydroxypregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our 9,11-Epoxypregn-4-Ene-17,21-Diol-3,20-Dione 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.