Description

6,9-Difluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione 21-Acetate is a high-purity synthetic steroid derivative, serving as a critical pharmaceutical intermediate. Its value lies in its precise chemical structure, which is essential for the development and manufacturing of advanced corticosteroid-based therapeutics. This compound is primarily required by pharmaceutical R&D laboratories and production facilities focused on anti-inflammatory and immunosuppressant drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent topical and systemic corticosteroids.
• Research & Development: Used in medicinal chemistry for developing new steroid-based drug candidates with modified pharmacological profiles.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral in multi-step synthesis processes for final API production under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Biochemical Research: Utilized in studies investigating steroid receptor interactions and metabolic pathways.

Basic Information

Item	Detail
Product Name	6,9-Difluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione 21-Acetate
CAS No.	4306-83-6
Molecular Formula	C23H28F2O6
Molecular Weight	438.47 g/mol
Synonyms	Difluprednate Impurity; Difluprednate Related Compound A; 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate; 6α,9α-Difluoroprednisolone 21-Acetate; 6,9-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate; 6,9-Difluoroprednisolone 21-Acetate; Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,16,17,21-tetrahydroxy-, 21-acetate
EINECS	Contact for details

Quality Control

Our 6,9-Difluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione 21-Acetate is manufactured and tested to meet stringent quality standards suitable for pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant pharmacopeial guidelines and support customer-specific validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.