Description

(S)-1-(Isopropylamino)-3-(Naphthyloxy)Propan-2-Ol CAS NO 4199-09-1 is a chiral organic compound featuring a naphthyloxy and an isopropylamino substituent on a propan-2-ol backbone, making it a valuable intermediate in asymmetric synthesis. Its primary commercial value lies in its role as a key chiral building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced material sectors seeking high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of β-adrenergic blocking agents (β-blockers) and other cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and development of chiral herbicides and pesticides where specific stereochemistry is required for biological activity.
• Asymmetric Catalyst Ligand: Serves as a precursor or framework for developing chiral ligands used in metal-catalyzed asymmetric reactions.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for research and industrial applications.
• Academic & Industrial R&D: A standard compound for methodological studies in organic chemistry, particularly in nucleophilic substitution and etherification reactions.

Basic Information

Product Name	(S)-1-(Isopropylamino)-3-(Naphthyloxy)Propan-2-Ol
CAS No.	4199-09-1
Molecular Formula	C₁₆H₂₁NO₂
Molecular Weight	259.34 g/mol
Synonyms	(S)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol; (S)-1-Isopropylamino-3-(naphth-1-yloxy)propan-2-ol; L-Propranolol Impurity; (S)-Propranolol Related Compound A; (S)-1-(Isopropylamino)-3-(1-naphthyloxy)propan-2-ol; (S)-1-(1-Naphthyloxy)-3-[(1-methylethyl)amino]-2-propanol; (S)-Naphthyloxypropanolamine; (S)-1-Naphthyloxy-3-isopropylaminopropan-2-ol
EINECS	Contact for details

Quality Control

Our production of (S)-1-(Isopropylamino)-3-(Naphthyloxy)Propan-2-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity and purity. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.