Description

Mitomycin A is a potent antibiotic and antitumor agent belonging to the mitomycin family of natural products. This compound is of significant interest in pharmaceutical research and development due to its ability to crosslink DNA, inhibiting cell proliferation. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery, biochemical studies, and the synthesis of novel therapeutic agents. Its unique mechanism of action makes it a critical tool for investigating DNA-damaging agents and developing new cancer therapies.

Application

• Pharmaceutical Research: As a key reference standard and active pharmaceutical ingredient (API) in oncology and antimicrobial research programs.
• Biochemical Studies: Used to study DNA alkylation and cross-linking mechanisms, cell cycle arrest, and apoptosis.
• Antitumor Agent Development: Serves as a lead compound or intermediate in the synthesis and evaluation of novel chemotherapeutic agents.
• Microbiological Research: Investigation of its potent antibiotic activity against various bacterial strains.
• Academic Research: A vital tool in university and institutional labs for cancer biology and molecular pharmacology studies.
• Quality Control: Employed as a certified reference material (CRM) for analytical method development and validation in QC laboratories.

Basic Information

Product Name	Mitomycin A
CAS No.	4055-39-4
Molecular Formula	C16H19N3O6
Molecular Weight	349.34 g/mol
Synonyms	Mitomycin A; Antibiotic MA 144A1; MA 144A1; 7-Amino-9α-methoxy-4,5,10-tris(oxiran-2-yl)-6-methyl-1,2,3,4,5,10-hexahydrobenzo[g]pteridine-8,11-dione; 6-Amino-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; Mitomycin A (MA 144A1); NSC 683193
EINECS	Contact for details

Quality Control

Our Mitomycin A is manufactured and controlled under a strict quality management system. Each batch undergoes rigorous analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by HPLC, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Dark purple to blue crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.