Description

Carbinoxamine is a first-generation ethanolamine antihistamine with potent H1 receptor antagonist activity. This compound is valued for its reliable pharmacological action and serves as a key intermediate in the synthesis of advanced pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for the development and production of antihistamine medications and related active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of antihistamine drugs and other therapeutic agents.
• Active Pharmaceutical Ingredient (API): Used in the formulation of finished dosage forms for allergy and cold symptom relief.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for novel histamine antagonists.
• Veterinary Pharmaceuticals: Employed in the development of antihistamine treatments for animal healthcare.
• Chemical Synthesis: Utilized as a specialized intermediate in custom synthesis and process development within fine chemical manufacturing.

Basic Information

Product Name	Carbinoxamine
CAS No.	486-16-8
Molecular Formula	C16H19ClN2O
Molecular Weight	290.79 g/mol
Synonyms	2-[(4-Chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine; Carbinoxamine Base; Histex; Ciberon; Allergefon; Clistin; Polistin; Andantol; Paracarbinoxamine
EINECS	207-633-0

Quality Control

Our Carbinoxamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.