Description

Ibogaine, o-Demethyl- is a naturally occurring psychoactive indole alkaloid and a key intermediate in the synthesis of various pharmaceutical compounds. Its significance lies in its structural role as a precursor for developing novel therapeutic agents targeting neurological pathways. This high-purity intermediate is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis specialists working on central nervous system (CNS) drug discovery and neuropharmacology studies.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of ibogaine derivatives and other complex indole alkaloids for preclinical and clinical research.
• Neurological Research: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in studies investigating addiction treatment, neuroregeneration, and psychopharmacology.
• Fine Chemical Synthesis: Utilized in organic synthesis for constructing complex molecular architectures in medicinal chemistry programs.
• Biochemical Research: Employed in in vitro assays to study receptor binding affinity and enzymatic interactions related to serotonin and other neurotransmitter systems.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related substances.

Basic Information

Product Name	Ibogaine, o-Demethyl-
CAS No.	481-88-9
Molecular Formula	C₁₉H₂₄N₂O
Molecular Weight	296.41 g/mol
Synonyms	12-Methoxyibogamine; Noribogaine; 12-Hydroxyibogamine; 10-Methoxyibogamine; Ibogaine metabolite; GM-110; O-Desmethylibogaine; 12-Methoxyibogamine
EINECS	Contact for details

Quality Control

Our Ibogaine, o-Demethyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via IR and MS. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and research requirements. Specifications are designed to meet the stringent needs of pharmaceutical R&D and can be tailored upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere if specified and kept in original packaging until use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.