Description

4-Fluorophenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its value lies in the strategic combination of the reactive cyano group and the electron-withdrawing fluorine substituent, enabling precise molecular construction. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors, CNS-active compounds, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Synthesis Building Block: Employed in various reactions such as nucleophilic substitution, reduction to amines, and hydrolysis to acids for constructing complex molecular architectures.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	4-Fluorophenylacetonitrile
CAS No.	459-29-4
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	(4-Fluorophenyl)acetonitrile; p-Fluorophenylacetonitrile; 4-Fluorobenzyl cyanide; 2-(4-Fluorophenyl)acetonitrile; (p-Fluorophenyl)acetonitrile; 4-Fluorobenzeneacetonitrile; α-Cyano-4-fluorotoluene; 459-29-4
EINECS	Contact for details

Quality Control

Our 4-Fluorophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. The product is stable under these conditions for extended periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.