Description

Methylamine, 1,1,1-Trifluoro-n-[2,2,2-Trifluoro-1-(Trifluoromethyl)Eth Ylidene]- is a highly fluorinated imine derivative, also known as Perfluorinated Ketimine, valued for its role as a versatile building block in advanced synthetic chemistry. Its unique structure, featuring multiple trifluoromethyl groups, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby enhancing their stability, lipophilicity, and biological activity. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used to create novel fluorinated herbicides, insecticides, and fungicides with improved environmental persistence and efficacy.
• Advanced Material Production: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with enhanced chemical and thermal resistance.
• Organic Synthesis Reagent: A valuable reagent in organofluorine chemistry for constructing complex molecules in academic and industrial research laboratories.
• Electrolyte Additive: Potential application in the formulation of advanced electrolytes for lithium-ion batteries to improve performance and safety.

Basic Information

Item	Details
Product Name	Methylamine, 1,1,1-Trifluoro-n-[2,2,2-Trifluoro-1-(Trifluoromethyl)Eth Ylidene]-
CAS No.	453-22-5
Molecular Formula	C5H2F9N
Molecular Weight	247.06 g/mol
Synonyms	Perfluorinated Ketimine; 1,1,1-Trifluoro-N-(2,2,2-trifluoro-1-(trifluoromethyl)ethylidene)methanamine; 2,2,2-Trifluoro-1-(trifluoromethyl)ethylidene(trifluoromethyl)amine; Hexafluoroacetone Trifluoromethylimine; (Perfluoro-tert-butyl)imine; F9-Ketimine; 453-22-5
EINECS	Contact for details

Quality Control

Our production of Methylamine, 1,1,1-Trifluoro-n-[2,2,2-Trifluoro-1-(Trifluoromethyl)Eth Ylidene]- adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture ingress and decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.6 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.