Description

4-Chloro-2-Nitro-1-(Trifluoromethoxy)Benzene is a specialized halogenated nitroaromatic compound that serves as a versatile and high-value building block in advanced chemical synthesis. Its unique structure, featuring chloro, nitro, and trifluoromethoxy substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and fungicides, leveraging the bioactivity of the trifluoromethoxy group.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aromatic systems into target molecules.
• Dye and Pigment Intermediate: Utilized in the production of specialized colorants and photographic chemicals.

Basic Information

Product Name	4-Chloro-2-Nitro-1-(Trifluoromethoxy)Benzene
CAS No.	448-38-4
Molecular Formula	C7H3ClF3NO3
Molecular Weight	241.55 g/mol
Synonyms	1-Chloro-4-(trifluoromethoxy)-2-nitrobenzene; 4-Chloro-2-nitro-1-(trifluoromethoxy)benzene; 2-Nitro-4-chloro-1-(trifluoromethoxy)benzene; 4-Chloro-α,α,α-trifluoro-2-nitroanisole; Benzene, 1-chloro-4-(trifluoromethoxy)-2-nitro-; 4-Chloro-2-nitroanisole, α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Nitro-1-(Trifluoromethoxy)Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.