Description

2-(4-Fluorophenyl)-3-Oxobutyronitrile is a versatile fluorinated organic intermediate with a reactive β-ketonitrile moiety. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic and pharmaceutical compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those containing fluorinated aromatic systems and heterocycles like pyrazoles and pyrimidines.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Organic Synthesis Building Block: Serves as a versatile synthon for constructing complex molecules via reactions at the ketone and nitrile functional groups, such as condensations, cyclizations, and nucleophilic additions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2-(4-Fluorophenyl)-3-Oxobutyronitrile
CAS No.	447-03-0
Molecular Formula	C10H8FNO
Molecular Weight	177.17 g/mol
Synonyms	4-Fluorobenzoylacetonitrile; 3-Oxo-2-(4-fluorophenyl)butanenitrile; 4'-Fluoro-2-oxobutyronitrile; 1-(4-Fluorophenyl)-3-oxobutanenitrile; 4-Fluorophenyl 3-oxobutyronitrile; 2-(p-Fluorophenyl)-3-oxobutyronitrile; 3-Oxo-2-(p-fluorophenyl)butyronitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-3-Oxobutyronitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment upon request, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.