Description

5-Fluoro-2-Nitrotoluene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent on the toluene ring, makes it a key building block for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for the synthesis of specialized fluorinated dyes and colorants.
• Material Science Research: Employed in the development of novel fluorinated polymers, liquid crystals, and electronic materials.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic aromatic substitutions, and reduction reactions to create more complex fluorinated compounds.

Basic Information

Product Name	5-Fluoro-2-Nitrotoluene
CAS No.	446-33-3
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	2-Nitro-5-fluorotoluene; 1-Fluoro-4-methyl-2-nitrobenzene; 5-Fluoro-2-methylnitrobenzene; 2-Methyl-4-fluoronitrobenzene; 4-Fluoro-2-nitrotoluene; 5-Fluoro-o-nitrotoluene; Toluene, 5-fluoro-2-nitro-
EINECS	207-173-7

Quality Control

Our 5-Fluoro-2-Nitrotoluene is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency. Key parameters such as assay (by HPLC), impurity profile, and physical properties are verified against stringent internal specifications. A Certificate of Analysis (COA) documenting these results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Ensure the container is kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	30 - 34 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.