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4-Fluoro-2-Nitrotoluene CAS NO 446-10-6


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CAS No.:446-10-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Fluoro-2-Nitrotoluene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluoro substituent on the toluene ring, makes it a key building block for the development of complex agrochemicals and pharmaceuticals. This compound is primarily sought after by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical industries for constructing more complex molecules.

Application

  • Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
  • Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and stability.
  • Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and pigments, leveraging the nitro group for further functionalization.
  • Material Science Research: Employed in the development of novel organic materials, including liquid crystals and polymers with specific electronic properties.
  • Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.
  • Chemical Research & Development: Utilized as a standard or building block in academic and industrial R&D for exploring new synthetic pathways.

Basic Information

Product Name 4-Fluoro-2-Nitrotoluene
CAS No. 446-10-6
Molecular Formula C7H6FNO2
Molecular Weight 155.13 g/mol
Synonyms 1-Fluoro-4-methyl-3-nitrobenzene; 2-Nitro-4-fluorotoluene; 4-Methyl-3-nitrofluorobenzene; 3-Nitro-4-fluorotoluene; 4-Fluoro-3-nitrotoluene; p-Fluoro-o-nitrotoluene; FNT
EINECS 207-173-1

Quality Control

Our 4-Fluoro-2-Nitrotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in research and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee reliable and traceable quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item Specification
Appearance Yellow to light brown crystalline powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 30 - 34 °C
Loss on Drying ≤ 0.5%
Related Substances (HPLC) Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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