Description

Benzene, 1,5-Difluoro-2-Methoxy-3-Nitro- is a high-purity, multi-functional aromatic building block distinguished by its unique substitution pattern of fluorine, methoxy, and nitro groups. This compound is critical for advanced organic synthesis, enabling the precise construction of complex molecules where regioselectivity and electronic properties are paramount. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms and nitro group contribute to biological activity and environmental persistence.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex, high-performance dyes and pigments due to its electron-withdrawing nitro and fluorine substituents.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cross-coupling reactions and nucleophilic aromatic substitution studies.

Basic Information

Product Name	Benzene, 1,5-Difluoro-2-Methoxy-3-Nitro-
CAS No.	441-31-6
Molecular Formula	C7H5F2NO3
Molecular Weight	189.12 g/mol
Synonyms	1,5-Difluoro-2-methoxy-3-nitrobenzene; 2-Methoxy-3,5-difluoronitrobenzene; 3,5-Difluoro-2-methoxynitrobenzene; 3-Nitro-1,5-difluoro-2-methoxybenzene; 3,5-Difluoro-2-nitroanisole; 2-Nitro-3,5-difluoroanisole; 441-31-6; 1,5-Difluoro-2-methoxy-3-nitro-benzene
EINECS	Contact for details

Quality Control

Every batch of Benzene, 1,5-Difluoro-2-Methoxy-3-Nitro- is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.