Description

2-Fluoro-3-Nitrotoluene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a nitro group on a toluene backbone, makes it a critical building block for the development of complex, high-value compounds. This product is essential for research and manufacturing chemists in the pharmaceutical and agrochemical industries seeking to introduce specific fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic rings for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a starting material for synthesizing fluorinated components used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the creation of specialized dyes and pigments, where the nitro group facilitates further chemical transformations into chromophores.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring novel fluorination reactions and constructing complex molecular architectures.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form biaryl structures.

Basic Information

Product Name	2-Fluoro-3-Nitrotoluene
CAS No.	437-86-5
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	1-Fluoro-2-methyl-3-nitrobenzene; 2-Methyl-3-nitrofluorobenzene; 3-Nitro-2-fluorotoluene; o-Fluoro-m-nitrotoluene; 2-Fluoro-3-nitromethylbenzene; 3-Nitro-2-fluoromethylbenzene; Benzene, 1-fluoro-2-methyl-3-nitro-
EINECS	207-125-5

Quality Control

Every batch of 2-Fluoro-3-Nitrotoluene is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing all critical parameters are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.