Description

(6S,8S,9S,10R,13R,14S,17S)-17-Acetyl-6-Fluoro-10,13-Dimethyl-2,6,7,8,9,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthrene-3,11-Dione is a high-purity, fluorinated steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for creating novel therapeutic agents, particularly due to the strategic incorporation of fluorine which can enhance metabolic stability and receptor binding affinity. It is essential for R&D chemists and process development scientists working in steroid chemistry, oncology, and endocrinology.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel fluorinated corticosteroid or hormone analogs with potential improved pharmacological profiles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to investigate the impact of fluorination at the 6-position on biological activity and metabolic pathways.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories producing or researching complex steroid molecules.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for advanced active pharmaceutical ingredients (APIs) within regulated environments.
• Biochemical Probes: Potential use in developing probes to study steroid hormone receptors and related enzymatic processes.

Basic Information

Item	Details
Product Name	(6S,8S,9S,10R,13R,14S,17S)-17-Acetyl-6-Fluoro-10,13-Dimethyl-2,6,7,8,9,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthrene-3,11-Dione
CAS No.	433-86-3
Molecular Formula	C₂₁H₂₅FO₄
Molecular Weight	360.42 g/mol
Synonyms	6-Fluoroandrost-4-ene-3,11,17-trione, 17-Acetyl; 6α-Fluoro-11-oxotestosterone 17-acetate; 6-Fluoro-11-oxotestosterone acetate; 17β-Acetoxy-6-fluoroandrost-4-ene-3,11-dione; 6-Fluoro-11-ketotestosterone acetate; 6-Fluoro-11-oxoandrost-4-ene-3,17-dione 17-acetate; 6-Fluoro-δ⁴-androstene-3,11,17-trione 17-acetate
EINECS	Contact for details

Quality Control

Our (6S,8S,9S,10R,13R,14S,17S)-17-Acetyl-6-Fluoro-10,13-Dimethyl-2,6,7,8,9,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthrene-3,11-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.