Description

Difluoronitroacetic Acid Methyl Ester is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and nitro groups, makes it a valuable precursor for introducing difluoronitroacetyl motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the difluoronitroacetyl group can enhance biological activity and stability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules, leveraging its reactivity for C-C and C-N bond formation.
• Fluorine Chemistry Research: Serves as a model compound or starting material in studies exploring the properties and reactivities of polyfluorinated nitro compounds.
• Material Science Precursor: Potential use in the synthesis of specialized fluorinated polymers or fine chemicals with unique surface properties.

Basic Information

Product Name	Difluoronitroacetic Acid Methyl Ester
CAS No.	428-13-7
Molecular Formula	C₃H₃F₂NO₄
Molecular Weight	155.06 g/mol
Synonyms	Methyl 2,2-difluoro-2-nitroacetate; Methyl difluoronitroacetate; 2,2-Difluoro-2-nitroacetic acid methyl ester; Difluoronitroacetic acid, methyl ester; Acetic acid, 2,2-difluoro-2-nitro-, methyl ester; Methyl (difluoronitro)acetate
EINECS	Contact for details

Quality Control

Our Difluoronitroacetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.