Description

Fluorometholone is a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties. It is a critical active pharmaceutical ingredient (API) valued for its effectiveness in managing inflammatory ocular conditions. This compound is primarily utilized by pharmaceutical manufacturers in the ophthalmic sector. Fluorometholone CAS NO 426-13-1 is a key component in the production of prescription eye drops and ointments.

Application

• Ophthalmic Anti-inflammatory Formulations: Primary use as the active ingredient in prescription eye drops and ointments for treating inflammation and swelling following eye surgery or due to conditions like uveitis.
• Allergic Conjunctivitis Treatment: Formulated into medications to relieve itching, redness, and swelling associated with ocular allergies.
• Vernal Keratoconjunctivitis Management: Used in specialized ophthalmic preparations to control severe allergic eye inflammation.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of more complex steroid derivatives for research and development.
• Veterinary Ophthalmology: Incorporated into topical preparations for treating inflammatory eye conditions in animals.
• Clinical Research: Used as a reference standard in analytical laboratories for method development, quality control, and pharmacokinetic studies.

Basic Information

Product Name	Fluorometholone
CAS No.	426-13-1
Molecular Formula	C22H29FO4
Molecular Weight	376.46 g/mol
Synonyms	9α-Fluoro-11β,17α-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione; 6α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; Fluorometholone; Flarex; FML; Oxylone; Flucon; Efflumidex; NSC-47439
EINECS	207-046-6

Quality Control

Our Fluorometholone is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure regulatory compliance and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.