Description

4-(Trifluoromethylthio)Nitrobenzene is a specialized fluorinated aromatic building block characterized by the presence of both a nitro group and a trifluoromethylthio substituent. This unique molecular structure makes it a valuable intermediate for synthesizing advanced agrochemicals and pharmaceuticals, where the introduction of fluorine and sulfur-containing groups is critical for modulating biological activity and physicochemical properties. It is primarily utilized by research and development chemists and process engineers in the fine chemical, agrochemical, and pharmaceutical industries.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethylthio group enhances lipophilicity and metabolic stability.
• Pharmaceutical Synthesis: Serves as a versatile building block for creating active pharmaceutical ingredients (APIs) and candidates, particularly in drug discovery programs targeting new therapeutic agents.
• Material Science Research: Used in the development of advanced materials, such as liquid crystals and organic semiconductors, due to its electron-withdrawing properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a substrate for further functionalization to create complex, multi-substituted benzene derivatives.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments that require nitro and sulfur-based functional groups.

Basic Information

Product Name	4-(Trifluoromethylthio)Nitrobenzene
CAS No.	403-66-7
Molecular Formula	C7H4F3NO2S
Molecular Weight	223.17 g/mol
Synonyms	1-Nitro-4-(trifluoromethylthio)benzene; p-(Trifluoromethylthio)nitrobenzene; 4-Nitro(trifluoromethylthio)benzene; α,α,α-Trifluoro-p-nitrothioanisole; Nitrophenyl trifluoromethyl sulfide; NSC 404087; 4-Trifluoromethylsulfanylnitrobenzene
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethylthio)Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of industrial and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.