Description

2-Hydroxy-2-(4-Fluorophenyl)Ethylamine Hydrochloride is a high-purity, synthetically valuable organic building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential central nervous system (CNS) agents, β-blockers, and other fluorinated bioactive molecules.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Asymmetric Synthesis: Used in the preparation of chiral amines and amino alcohols due to its defined stereochemistry, applicable in catalyst and ligand development.
• Reference Standard: Employed as an analytical standard in quality control (QC) and method development for pharmaceutical manufacturing processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.

Basic Information

Product Name	2-Hydroxy-2-(4-Fluorophenyl)Ethylamine Hydrochloride
CAS No.	403-28-1
Molecular Formula	C8H11ClFNO
Molecular Weight	191.63 g/mol
Synonyms	1-(4-Fluorophenyl)-2-aminoethanol Hydrochloride; 2-Amino-1-(4-fluorophenyl)ethanol Hydrochloride; 4-Fluoro-α-(aminomethyl)benzyl Alcohol Hydrochloride; (R/S)-2-Amino-2-(4-fluorophenyl)ethanol Hydrochloride; Norfenefrine Impurity C Hydrochloride; p-Fluoro-2-amino-1-phenylethanol Hydrochloride; α-(Aminomethyl)-4-fluorobenzyl Alcohol Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-(4-Fluorophenyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.