Description

4-Nitrobenzotrifluoride is a versatile fluorinated aromatic nitro compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the nitro group and the stability imparted by the trifluoromethyl substituent, enabling precise chemical transformations. This intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic structures for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the trifluoromethyl group improves compound efficacy and environmental profile.
• Dye and Pigment Manufacturing: Serves as a starting material for producing high-performance, light-fast dyes and organic pigments.
• Liquid Crystal and Electronic Materials: A valuable intermediate for creating fluorinated components used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer chains, enhancing material properties like chemical resistance and thermal stability.
• Organic Synthesis Research: A fundamental reagent in academic and industrial R&D for exploring novel nucleophilic aromatic substitution reactions and cross-coupling methodologies.

Basic Information

Product Name	4-Nitrobenzotrifluoride
CAS No.	402-54-0
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	α,α,α-Trifluoro-4-nitrotoluene; 4-Nitro-α,α,α-trifluorotoluene; p-Nitrobenzotrifluoride; 1-Nitro-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)nitrobenzene; p-Nitrophenyltrifluoromethane; Benzene, 1-nitro-4-(trifluoromethyl)-; NSC 1769
EINECS	206-941-2

Quality Control

Our 4-Nitrobenzotrifluoride is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	34°C - 38°C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.