Description

3-Chloro-5-Nitrobenzotrifluoride is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and trifluoromethyl groups, makes it an essential intermediate for creating complex molecules with tailored properties. This high-purity intermediate is primarily sought by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for developing novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and trifluoromethyl motifs.
• Pharmaceutical Synthesis: Used as a building block for creating active pharmaceutical ingredients (APIs), particularly in the development of compounds requiring specific halogenated aromatic cores.
• Dye and Pigment Manufacturing: Serves as an intermediate in the production of specialized dyes and pigments, where the nitro group aids in color development.
• Material Science Research: Employed in academic and industrial R&D for synthesizing novel organic materials, including liquid crystals and polymers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures common in advanced chemistry.

Basic Information

Product Name	3-Chloro-5-Nitrobenzotrifluoride
CAS No.	401-93-4
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	1-Chloro-3-nitro-5-(trifluoromethyl)benzene; 3-Chloro-5-nitro-α,α,α-trifluorotoluene; 3-Chloro-α,α,α-trifluoro-5-nitrotoluene; 5-Nitro-3-chlorobenzotrifluoride; Benzene, 1-chloro-3-nitro-5-(trifluoromethyl)-; m-Chloro-m-nitrobenzotrifluoride
EINECS	206-936-6

Quality Control

Our 3-Chloro-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.