Description

4-Iodo-3-Nitrobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring iodine, nitro, and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and trifluoromethyl groups.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials due to its ability to influence molecular polarity and mesomorphic properties.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Functional Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where electron-withdrawing groups are required for color and stability tuning.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Iodo-3-Nitrobenzotrifluoride
CAS No.	400-97-5
Molecular Formula	C7H3F3INO2
Molecular Weight	316.99 g/mol
Synonyms	1-Iodo-2-nitro-4-(trifluoromethyl)benzene; 2-Nitro-α,α,α-trifluoro-4-iodotoluene; 4-Iodo-3-nitro-α,α,α-trifluorotoluene; 3-Nitro-4-iodobenzotrifluoride; Benzene, 1-iodo-2-nitro-4-(trifluoromethyl)-; Iodo-nitro-benzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-Iodo-3-Nitrobenzotrifluoride is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.