Description

Formestane is a potent and selective steroidal aromatase inhibitor, a critical compound in pharmaceutical research and development. Its primary value lies in its ability to specifically inhibit the aromatase enzyme, which is responsible for the synthesis of estrogens from androgens. This makes it an essential intermediate and reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing therapies related to hormone-dependent conditions.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Serves as a key intermediate in the synthesis of advanced therapeutic agents.
• Biochemical Research: Used as a potent and selective reference standard in studies of aromatase enzyme kinetics and inhibition mechanisms.
• Oncology Research: Investigated for its potential application in hormone-dependent cancer research programs.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related substances.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental endocrinology and steroid metabolism studies.

Basic Information

Item	Detail
Product Name	Formestane
CAS No.	48-35-1
Molecular Formula	C19H26O3
Molecular Weight	302.41 g/mol
Synonyms	4-Hydroxyandrost-4-ene-3,17-dione; 4-Hydroxyandrostenedione; 4-OHA; Lentaron; CGP-32349; Formestanum; NSC-331561; 4-Hydroxy-4-androstene-3,17-dione
EINECS	200-200-5

Quality Control

Our Formestane is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, related substances, and residual solvents. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.