Description

4-Fluorophenyl Lactonitrile is a specialized fluorinated organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and high-performance agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. Industries requiring precise, high-purity intermediates for research and production, particularly in pharmaceuticals, agrochemicals, and advanced material science, will find this product essential. Its unique structure facilitates complex molecular transformations, enabling the creation of novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorophenyl group contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic components in electronic display and lighting materials.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D for constructing complex molecules via cyano and lactone chemistry.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, dyes, and functional materials requiring specific fluorinated aromatic structures.

Basic Information

Product Name	4-Fluorophenyl Lactonitrile
CAS No.	393781-55-0
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	4-Fluorobenzylidenemalononitrile oxide; 2-(4-Fluorobenzylidene)-3-oxopropanenitrile; (4-Fluorophenyl)(hydroxy)malononitrile; Lactonitrile, 4-fluorophenyl-; 4-Fluorophenyl(hydroxy)malononitrile; 4-Fluorobenzaldehyde cyanohydrin acetate (related derivative); α-Hydroxy-4-fluorobenzeneacetonitrile (cyclic form)
EINECS	Contact for details

Quality Control

Our 4-Fluorophenyl Lactonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of our global clientele in regulated industries. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.