Description

Benzonitrile, 4-(2-Aminoethyl)-2-Fluoro- (9Ci) CAS NO 380607-86-3 is a high-purity, fluorinated aromatic nitrile derivative featuring a primary amine functional group, making it a versatile and valuable building block in advanced organic synthesis. Its molecular structure is specifically engineered to serve as a key intermediate in the development of complex, high-value chemical entities. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for constructing novel molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom and amine group can enhance biological activity and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into the synthesis of specialty polymers, dyes, and liquid crystals to modify thermal stability, solubility, and optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and fluorescent tags for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Benzonitrile, 4-(2-Aminoethyl)-2-Fluoro- (9Ci)
CAS No.	380607-86-3
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	4-(2-Aminoethyl)-2-fluorobenzonitrile; 2-Fluoro-4-(2-aminoethyl)benzonitrile; 2-Fluoro-4-(2-aminoethyl)benzonitrile; 4-(2-Aminoethyl)-2-fluorobenzonitrile; 380607-86-3; 4-(2-Aminoethyl)-2-fluorobenzonitrile (9CI); Benzonitrile, 4-(2-aminoethyl)-2-fluoro- (9CI)
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-(2-Aminoethyl)-2-Fluoro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our commitment to quality supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.