Description

3-(4-Fluorophenyl)-3-(Furan-2-Yl)Propanenitrile is a specialized organic building block featuring a unique molecular scaffold combining fluorophenyl and furan moieties. This compound is of significant value in advanced organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. It serves as a critical intermediate for researchers and process chemists in the fine chemical, pharmaceutical R&D, and agrochemical industries seeking to incorporate complex, functionalized structures into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, where the fluorine atom and heterocyclic structure can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where its conjugated system is beneficial.
• Academic & Contract Research: An essential reagent for universities and CROs (Contract Research Organizations) conducting methodological studies in synthetic organic chemistry, including cross-coupling and cyclization reactions.
• Fluorine Chemistry: A valuable compound for exploring structure-activity relationships (SAR) in medicinal chemistry due to the presence of the fluorine substituent.

Basic Information

Product Name	3-(4-Fluorophenyl)-3-(Furan-2-Yl)Propanenitrile
CAS No.	374918-00-0
Molecular Formula	C₁₃H₁₀FNO
Molecular Weight	215.22 g/mol
Synonyms	3-(4-Fluorophenyl)-3-(2-furyl)propanenitrile; 3-(4-Fluorophenyl)-3-(furan-2-yl)propanenitrile; 2-[2-Cyano-1-(4-fluorophenyl)ethyl]furan; 374918-00-0; 3-(4-Fluorophenyl)-3-(2-furanyl)-Propanenitrile; Propanenitrile, 3-(4-fluorophenyl)-3-(2-furanyl)-; 3-(4-Fluorophenyl)-3-(furan-2-yl)propionitrile
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-3-(Furan-2-Yl)Propanenitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.