Description

1,4-Dibromo-2-Fluoro-5-Nitrobenzene is a high-purity halogenated nitrobenzene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen and nitro functional groups for bioactivity or further derivatization.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and insecticides, where its halogen atoms are instrumental in creating compounds with specific modes of action.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, facilitating the construction of complex biaryl and heterocyclic structures.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments, where the nitro and halogen groups influence color properties and fastness.
• Chemical Biology Probes: Used to create tagged molecules or affinity probes for studying biological pathways and protein interactions in research settings.

Basic Information

Product Name	1,4-Dibromo-2-Fluoro-5-Nitrobenzene
CAS No.	366496-33-5
Molecular Formula	C6H2Br2FNO2
Molecular Weight	298.89 g/mol
Synonyms	2-Fluoro-1,4-dibromo-5-nitrobenzene; 1,4-Dibromo-2-fluoro-5-nitrobenzene; Benzene, 1,4-dibromo-2-fluoro-5-nitro-; 5-Nitro-1,4-dibromo-2-fluorobenzene; 2-Fluoro-5-nitro-1,4-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,4-Dibromo-2-Fluoro-5-Nitrobenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports traceability and meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.