Description

3,3'-Difluoro-[1,1'-Biphenyl]-4,4'-Dicarbonitrile is a high-purity, fluorinated biphenyl derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in the unique electronic and steric properties imparted by the fluorine atoms and nitrile groups, making it a versatile building block for complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluorobiphenyl core contributes to bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a fundamental building block for fluorine-containing liquid crystal molecules and organic light-emitting diode (OLED) materials, enhancing electronic properties and device performance.
• Polymer & Advanced Material Science: Incorporated into specialty polymers, high-performance resins, and advanced organic frameworks to modify thermal stability, chemical resistance, and optical characteristics.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct more complex conjugated systems.
• Organic Electronic Materials: Used in the synthesis of electron-transport materials and n-type semiconductors for organic photovoltaics and field-effect transistors.

Basic Information

Product Name	3,3'-Difluoro-[1,1'-Biphenyl]-4,4'-Dicarbonitrile
CAS No.	359813-00-6
Molecular Formula	C14H6F2N2
Molecular Weight	240.21 g/mol
Synonyms	3,3'-Difluoro-4,4'-biphenyldicarbonitrile; 4,4'-Dicyano-3,3'-difluorobiphenyl; [1,1'-Biphenyl]-4,4'-dicarbonitrile, 3,3'-difluoro-; 3,3'-Difluorobiphenyl-4,4'-dicarbonitrile; 3,3'-Difluoro-4,4'-dicyanobiphenyl; 3,3'-Difluoro[1,1'-biphenyl]-4,4'-dicarbonitrile; 3,3'-Difluoro-4,4'-biphenyldinitrile
EINECS	Contact for details

Quality Control

Our 3,3'-Difluoro-[1,1'-Biphenyl]-4,4'-Dicarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.