Description

Benzonitrile, 5-Fluoro-2-Hydroxy-4-Methyl- (9Ci) is a specialized fluorinated aromatic nitrile derivative, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring both a nitrile and a hydroxyl group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic and polar characteristics.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential substrate for studying fluorination reactions and the structure-activity relationships (SAR) of fluorinated aromatic compounds.
• Fine Chemical Production: Utilized in the custom synthesis of dyes, pigments, and other specialty chemicals requiring specific fluorinated aromatic backbones.

Basic Information

Product Name	Benzonitrile, 5-Fluoro-2-Hydroxy-4-Methyl- (9Ci)
CAS No.	357404-55-8
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	5-Fluoro-2-hydroxy-4-methylbenzonitrile; 2-Hydroxy-5-fluoro-4-methylbenzonitrile; 4-Methyl-5-fluoro-2-hydroxybenzonitrile; 5-Fluoro-4-methyl-2-hydroxybenzonitrile; 2-Cyano-4-fluoro-5-methylphenol; 5-Fluoro-2-hydroxy-p-tolunitrile; 5-Fluoro-4-methylsalicylonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 5-Fluoro-2-Hydroxy-4-Methyl- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.