Description

(R)-1,1-Diphenyl-1-Fluoro-2-Aminopropane CAS NO 352534-91-9 is a chiral, fluorinated amine building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a stereogenic center with fluorine and amine functionalities, enabling the construction of complex, biologically active molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in enantioselective catalysis.
• Agrochemical Research: Used in the discovery and synthesis of new, more effective pesticides and herbicides with potentially improved selectivity.
• Fluorine Chemistry Studies: An important compound for academic and industrial research exploring the effects of fluorine substitution on molecular properties and bioactivity.
• Peptidomimetic Synthesis: Employed in the design and construction of peptide analogs where the fluorine atom and chiral center are used to modulate stability and receptor binding.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or surface properties.

Basic Information

Product Name	(R)-1,1-Diphenyl-1-Fluoro-2-Aminopropane
CAS No.	352534-91-9
Molecular Formula	C15H16FN
Molecular Weight	229.29 g/mol
Synonyms	(R)-1-Amino-1-fluoro-2,2-diphenylpropane; (R)-1-Fluoro-2-amino-1,1-diphenylpropane; (R)-α-Fluoro-β-aminodiphenylpropane; (R)-F-Deprenylamine; (R)-1,1-Diphenyl-1-fluoro-2-propanamine; (R)-Norephedrine, 1-fluoro-1,1-diphenyl-; (R)-Fenfluramine Impurity; (R)-1-Fluoro-1,1-diphenyl-2-propylamine
EINECS	Contact for details

Quality Control

Our (R)-1,1-Diphenyl-1-Fluoro-2-Aminopropane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards of research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.