Description

2-Fluoro-5-Iodobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry for creating fluorinated and iodinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in cross-coupling reactions and catalysis.
• Functional Material Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom chemical synthesis services targeting niche and high-value products.

Basic Information

Product Name	2-Fluoro-5-Iodobenzonitrile
CAS No.	351003-36-6
Molecular Formula	C7H3FIN
Molecular Weight	262.01 g/mol
Synonyms	5-Iodo-2-fluorobenzonitrile; 2-Fluoro-5-iodobenzene carbonitrile; Benzonitrile, 2-fluoro-5-iodo-; 351003-36-6; 2-Fluoro-5-iodo-benzonitrile; 5-Iodo-2-fluoro-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Iodobenzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.