Description

(R)-B-Amino-4-Fluorobenzenepropanol CAS NO 348619-91-0 is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its enantiomeric purity, which is critical for the development of active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, optically active pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand in chiral catalysis for producing other high-value enantiopure compounds.
• Academic & Contract Research: Essential for medicinal chemistry research, process development, and scale-up studies in academic and CRO/CMO settings.
• Fine Chemical Production: Building block for advanced materials, liquid crystals, and other specialty organic compounds requiring fluorinated aromatic structures.

Basic Information

Product Name	(R)-B-Amino-4-Fluorobenzenepropanol
CAS No.	348619-91-0
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	(R)-3-Amino-3-(4-fluorophenyl)-1-propanol; (R)-3-Amino-3-(4-fluorophenyl)propan-1-ol; (R)-β-Amino-4-fluorobenzenepropanol; (R)-3-(4-Fluorophenyl)-3-aminopropan-1-ol; (R)-FPPA; (R)-FPP-OH; (R)-4-Fluoro-β-aminobenzenepropanol; Benzenepropanol, β-amino-4-fluoro-, (R)-
EINECS	Contact for details

Quality Control

Our (R)-B-Amino-4-Fluorobenzenepropanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.