Description

6-[(2-Fluoroanilino)Carbonyl]-3-Cyclohexene-1-Carboxylic Acid is a high-value, fluorinated organic building block characterized by its cyclohexene carboxylic acid core and a 2-fluoroanilino carbonyl substituent. This compound matters for its role as a sophisticated intermediate in the synthesis of complex molecules, offering chemists a versatile handle for further functionalization. It is primarily needed by research and development teams in the pharmaceutical and advanced agrochemical sectors, where it serves as a critical precursor for creating novel active ingredients with potential enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated aromatic motifs to modulate pharmacokinetics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, or insecticides where the fluorine atom can improve efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex heterocycles or functionalized cyclohexane derivatives.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or advanced organic materials requiring specific fluorinated components.
• Ligand and Catalyst Development: Can be utilized to develop novel chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	6-[(2-Fluoroanilino)Carbonyl]-3-Cyclohexene-1-Carboxylic Acid
CAS No.	346446-20-6
Molecular Formula	C14H14FNO3
Molecular Weight	263.26 g/mol
Synonyms	3-Cyclohexene-1-carboxylic acid, 6-[(2-fluoroanilino)carbonyl]-; 6-[(2-Fluorophenyl)carbamoyl]cyclohex-3-ene-1-carboxylic acid; 2-Fluoro-N-(4-carboxy-2-cyclohexen-1-yl)benzamide; (1R,6S)-6-[(2-Fluoroanilino)carbonyl]-3-cyclohexene-1-carboxylic acid (for chiral forms); FCAA Intermediate; CAS 346446-20-6
EINECS	Contact for details

Quality Control

Our 6-[(2-Fluoroanilino)Carbonyl]-3-Cyclohexene-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), impurity profiles, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.