Description

4,4,4-Trifluoro-1-Morpholino-1,3-Butanedione is a high-value fluorinated β-diketone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a morpholine moiety, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and anti-infective agents.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a chelating agent for metal ions in the preparation of catalysts for asymmetric synthesis and polymerization reactions.
• Material Science Research: Building block for fluorinated polymers, liquid crystals, and organic electronic materials requiring specific solubility and electronic characteristics.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	4,4,4-Trifluoro-1-Morpholino-1,3-Butanedione
CAS No.	338792-91-9
Molecular Formula	C8H10F3NO3
Molecular Weight	225.17 g/mol
Synonyms	4,4,4-Trifluoro-1-(morpholin-4-yl)butane-1,3-dione; 1-Morpholino-4,4,4-trifluorobutane-1,3-dione; 4,4,4-Trifluoro-3-oxo-1-morpholinobutan-1-one; 4-Morpholino-1,1,1-trifluoro-2,4-butanedione; TFMB; Trifluoromethylated Morpholino Diketone
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-1-Morpholino-1,3-Butanedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.