Description

trans-2,6-Difluoro-4-(4-Vinyl-Cyclohexyl)-Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated aromatic and vinyl-substituted cyclohexyl structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), where its specific stereochemistry and functional groups enable precise molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and advanced materials sectors, particularly those developing next-generation therapeutics and specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Liquid Crystal Material Precursor: Serves as a core component in the production of advanced liquid crystal mixtures for display technologies.
• Organic Synthesis Building Block: Used in cross-coupling reactions and other organic transformations to introduce the difluorobenzonitrile moiety into complex molecules.
• Agrochemical Research: Employed in the research and development of new agrochemicals, such as herbicides and pesticides, leveraging its fluorinated aromatic system.
• Polymer Modification: The vinyl group allows for incorporation into polymer chains, enabling the creation of specialty polymers with tailored optical or electronic properties.
• Material Science Research: Investigated for use in organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	trans-2,6-Difluoro-4-(4-Vinyl-Cyclohexyl)-Benzonitrile
CAS No.	337366-98-0
Molecular Formula	C15H15F2N
Molecular Weight	247.29 g/mol
Synonyms	4-(4-Ethenylcyclohexyl)-2,6-difluorobenzonitrile; 2,6-Difluoro-4-(4-vinylcyclohexyl)benzonitrile; Benzonitrile, 2,6-difluoro-4-(4-ethenylcyclohexyl)-; 4-(trans-4-Vinylcyclohexyl)-2,6-difluorobenzonitrile; trans-4-(2,6-Difluoro-4-cyanophenyl)vinylcyclohexane; (trans)-2,6-Difluoro-4-(4-vinylcyclohexyl)benzonitrile; LC-242
EINECS	Contact for details

Quality Control

Our trans-2,6-Difluoro-4-(4-Vinyl-Cyclohexyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Isomeric Purity (trans-isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.