Description

1-Bromo-2-Fluoro-5-Methoxy-4-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by R&D chemists and process development scientists for creating active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in fluorinated and brominated active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials.
• Dyestuff and Pigment Intermediate: Facilitates the synthesis of specialized, high-performance colorants.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Academic and Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in heterocyclic and medicinal chemistry.

Basic Information

Item	Details
Product Name	1-Bromo-2-Fluoro-5-Methoxy-4-Nitrobenzene
CAS No.	330794-02-0
Molecular Formula	C7H5BrFNO3
Molecular Weight	250.02 g/mol
Synonyms	2-Bromo-1-Fluoro-4-Methoxy-5-Nitrobenzene; 4-Bromo-5-Fluoro-2-Methoxy-1-Nitrobenzene; 5-Bromo-4-Fluoro-2-Methoxy-1-Nitrobenzene; 1-Bromo-2-fluoro-5-methoxy-4-nitro-benzene; Benzene, 1-bromo-2-fluoro-5-methoxy-4-nitro-; 330794-02-0
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-5-Methoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.